has material basis in germline mutation in LEMD3 syndromic disease skeletal system disorder Buschke-Ollendorff syndrome https://github.com/monarch-initiative/mondo/issues/4521 https://github.com/monarch-initiative/mondo/issues/4948 https://github.com/monarch-initiative/mondo/issues/5682 https://github.com/monarch-initiative/mondo/issues/6751 https://www.malacards.org/card/buschke_ollendorff_syndrome icd11.foundation:1556522143 Bos OMIM:166700 MONDO:0008157 MESH:C537415 osteopoikilosis with or without melorheostosis DOID:0111536 UMLS:C0265514 MEDGEN:120545 Buschke Ollendorff syndrome GARD:0027355 Buschke-Ollendorff syndrome Buschke-Ollendorff syndrome (BOS) is a benign disorder characterized by the association of osteopoikilosis lesions (``spotted bones'') in the skeleton and connective tissue nevi in the skin. Orphanet:1306 dermatofibrosis, disseminated with osteopoikilosis osteopetrosis obsolete dermis elastic tissue disorder laminopathy