extramammary Paget disease A malignant neoplasm in which there is infiltration of the skin by neoplastic large cells with abundant pale cytoplasm and large nuclei with prominent nucleoli (Paget cells). It may affect the anus, penis, scrotum, and vulva. Paget's disease of the skin OMIM:167300 Extramammary Paget's disease MESH:D010145 Orphanet:2800 GARD:0004192 MONDO:0008177 Paget's disease of skin ONCOTREE:EMPD Paget disease, EXTRAMAMMARY icd11.foundation:1796624917 Paget disease Extramammary EMPD MEDGEN:45280 NCIT:C3302 EFO:1000249 cutaneous Paget's disease ICDO:8542/3 UMLS:C0030186 MedDRA:10033366 extramammary Paget disease Paget's skin disease MedDRA:10068223 obsolete rare skin tumor or hamartoma Paget disease