has characteristic has characteristic has material basis in germline mutation in SDHD Autosomal dominant inheritance autosomal dominant disease paraganglioma pheochromocytoma/paraganglioma syndrome 1 https://github.com/monarch-initiative/mondo/issues/4521 https://github.com/monarch-initiative/mondo/issues/9178 https://www.malacards.org/card/pheochromocytoma_paraganglioma_syndrome_1 An autosomal dominant tumor predisposition disorder caused by pathogenic variants in the SDHD gene, characterized by an increased risk of paraganglioma and pheochromocytoma, as well as an increased risk of renal cell carcinoma and gastrointestinal stromal tumors (GIST). PGL1 GARD:0007324 MEDGEN:488134 pheochromocytoma/paraganglioma syndrome 1 glomus jugulare tumours paraganglioma caused by mutation in SDHD paragangliomas 1, with or without deafness SDHD paraganglioma OMIM:168000 paragangliomas 1 paragangliomas type 1 carotid body tumours MONDO:0008192 SDHD-related tumor predisposition DOID:0061216 UMLS:C3494181 hereditary neoplastic syndrome hereditary pheochromocytoma-paraganglioma