has material basis in germline mutation in HOXA13 syndromic disease hereditary disease Guttmacher syndrome https://github.com/monarch-initiative/mondo/issues/6876 https://github.com/monarch-initiative/mondo/issues/6878 https://www.malacards.org/card/preaxial_deficiency_postaxial_polydactyly_and_hypospadias_2 OMIM:176305 MEDGEN:401304 UMLS:C1867801 MESH:C538278 GARD:0004470 autosomal dominant preaxial deficiency, postaxial polydactyly, and hypospadias MONDO:0008301 Guttmacher syndrome is an extremely rare syndrome characterized by hypoplastic thumbs and halluces, 5th finger clinobrachydactyly, postaxial polydactyly of the hands, short or uniphalangeal 2nd toes with absent nails and hypospadias. preaxial deficiency-postaxial polydactyly-hypospadias syndrome Orphanet:2957 SCTID:722452004 preaxial deficiency, postaxial polydactyly and hypospadias Guttmacher syndrome DOID:0111544