has material basis in germline mutation in LOXL1 phacogenic glaucoma syndromic disease iris disorder exfoliation syndrome https://github.com/monarch-initiative/mondo/issues/4521 https://github.com/monarch-initiative/mondo/issues/4882 https://www.malacards.org/card/exfoliation_syndrome SCTID:111514006 EFO:0004235 Orphanet:529819 UMLS:C0206368 MEDGEN:60133 MESH:D017889 GARD:0027786 ICD9:365.52 An autosomal dominant disorder caused by mutations in the LOXL1 gene, encoding lysyl oxidase homolog 1. The condition is characterized by abnormal fibrillar extracellular material in anterior segment tissues, and may lead to glaucoma. pseudoexfoliation glaucoma XFS DOID:13641 MONDO:0008327 NCIT:C129025 XFG hereditary glaucoma