has material basis in germline mutation in PLAG1 benign digestive system neoplasm hereditary disease pleomorphic adenoma https://github.com/monarch-initiative/mondo/issues/4521 https://www.malacards.org/card/pleomorphic_adenoma https://www.malacards.org/card/salivary_gland_adenoma_pleomorphic DOID:452 UMLS:C1519176 pleomorphic adenoma GARD:0017789 MESH:D008949 pleomorphic adenoma (morphologic abnormality) MONDO:0008401 OMIM:181030 mixed tumour of the salivary gland ICDO:8940/0 tumor, mixed, benign Orphanet:454821 MEDGEN:275400 SCTID:447888006 adenomas, salivary gland pleomorphic, somatic A neoplasm characterized by the presence of benign epithelial and myoepithelial cells and a mesenchymal component that may contain mucoid, myxoid, cartilaginous, or osseous areas. It may be completely or partially encapsulated. It occurs in the parotid gland, submandibular gland, minor salivary glands in the oral cavity, upper respiratory tract, and nasal cavity and paranasal sinuses. It usually presents as a slow growing painless mass. Infrequently, patients may present with pain and facial palsy. It may recur after excision or transform to a malignant neoplasm (carcinoma ex pleomorphic adenoma). NCIT:C8602 benign epithelial tumor of salivary glands mixed neoplasm