flat face-microstomia-ear anomaly syndrome https://www.malacards.org/card/flat_face_microstomia_ear_anomaly_syndrome https://www.malacards.org/card/simosa_craniofacial_syndrome GARD:0004873 blepharophimosis-telecanthus-microstomia syndrome OMIM:182150 MESH:C537339 UMLS:C1866962 MONDO:0008421 Orphanet:1968 Simosa cranio facial syndrome MEDGEN:356655 Flat face-microstomia-ear anomaly syndrome is a rare, genetic, multiple congenital anomalies/dysmorphic syndrome characterized by dysmorphic facial features, including high forehead, elongated and flattened midface, arched and sparse eyebrows, short palpebral fissures, telecanthus, long nose with hypoplastic nostrils, long philtrum, high and narrow palate and microstomia with downturned corners. Ears are characteristically malformed, large, low-set and posteriorly rotated and nasal speech is associated. There have been no further descriptions in the literature since 1994. Simosa-Penchaszadeh-Bustos syndrome multiple congenital anomalies/dysmorphic syndrome without intellectual disability