syndromic intellectual disability syndromic disease Czeizel-Losonci syndrome https://github.com/monarch-initiative/mondo/issues/5588 https://github.com/monarch-initiative/mondo/issues/6878 https://www.malacards.org/card/split_hand_with_obstructive_uropathy_spina_bifida_and_diaphragmatic_defects split hand-urinary anomalies-spina bifida syndrome MESH:C566662 MEDGEN:401071 MONDO:0008467 OMIM:183802 Orphanet:2437 Czeizel-Losonci syndrome (CLS) is an exceedingly rare, severe, congenital genetic malformation disorder characterized by split hand/split foot, hydronephrosis, and spina bifida. Spinal and skeletal manifestations were thoracolumbar scoliosis, spinabifida (spina bifida occulta or spina bifida cystic), Bochdalek diaphragmatic hernia, and radial defects.There have been no further descriptions in the literature since 1987. split hand urinary anomalies spina bifida split hand with obstructive uropathy, spina bifida and diaphragmatic defects GARD:0004969 UMLS:C1866739 multiple congenital anomalies/dysmorphic syndrome without intellectual disability