has material basis in germline mutation in TSC1 tuberous sclerosis tuberous sclerosis 1 https://github.com/monarch-initiative/mondo/issues/4521 https://github.com/monarch-initiative/mondo/issues/9178 GARD:0015121 TSC1 tuberous sclerosis type 1 MONDO:0008612 tuberous sclerosis 1 DOID:0080324 tuberous sclerosis caused by mutation in TSC1 TSC1 tuberous sclerosis NCIT:C75122 UMLS:C1854465 OMIM:191100 An autosomal dominant syndrome caused by pathogenic variants in the TSC1 gene, characterized by the growth of hamartomas in multiple organs, including the brain, skin, kidneys, heart, and lungs. Other clinical features include seizures, intellectual disability, and skin lesions. MESH:C565346 tuberous sclerosis-1 tuberous sclerosis, type 1 MEDGEN:344288 TSC1-related tuberous sclerosis obsolete tuberous sclerosis complex