has material basis in germline mutation in disease has basis in disruption of disease caused by disruption of ACADS short-chain fatty acyl-CoA dehydrogenase activity hereditary disease short chain acyl-CoA dehydrogenase deficiency https://rarediseases.info.nih.gov/diseases/4822/short-chain-acyl-coa-dehydrogenase-deficiency https://www.malacards.org/card/acyl_coa_dehydrogenase_short_chain_deficiency_of SCADD icd11.foundation:180018315 Short Chain Acyl CoA Dehydrogenase Deficiency MEDGEN:90998 MESH:C537596 acyl-CoA dehydrogenase, short-chain, deficiency OF Short-chain acyl-CoA dehydrogenase (SCAD) deficiency is a very rare inborn error of mitochondrial fatty acid oxidation characterized by variable manifestations ranging from asymptomatic individuals (in most cases) to those with failure to thrive, hypotonia, seizures, developmental delay and progressive myopathy. short-chain acyl-Coenzyme A dehydrogenase deficiency (SCAD) short-chain acyl-coenzyme A dehydrogenase deficiency DOID:0080154 short chain acyl-CoA dehydrogenase deficiency ACADS deficiency ICD10CM:E71.312 OMIM:201470 SCAD NCIT:C84539 acyl-CoA dehydrogenase, short-chain deficiency NANDO:2200514 MONDO:0008722 short-chain acyl-CoA dehydrogenase deficiency Orphanet:26792 SCAD deficiency short-chain acyl-CoA dehydrogenase deficiency (SCAD) GARD:0004822 UMLS:C0342783 ACADSD NORD:1709 acyl-CoA dehydrogenase deficiency