has material basis in germline mutation in HR alopecia, isolated alopecia universalis congenita https://www.malacards.org/card/alopecia_universalis_congenita UMLS:C1859877 MONDO:0008757 Orphanet:701 MEDGEN:349262 GARD:0000614 The most severe form of alopecia areata, an inflammatory disease of the hair follicle, which is characterized by a complete loss of hair of the scalp and all the hair-bearing areas of the body. MedDRA:10001767 alopecia areata universalis DOID:0050634 MESH:C537055 AU atrichia, generalized atrichia, generalised ICD9:704.09 SCTID:86166000 ALUNC OMIM:203655 alopecia universalis congenita