has material basis in germline mutation in disease arises from feature disease has basis in feature TMPRSS6 Abnormality of iron homeostasis microcytic anemia IRIDA syndrome https://www.malacards.org/card/iron_refractory_iron_deficiency_anemia Orphanet:209981 GARD:0010957 MEDGEN:39081 MONDO:0008788 IRIDA OMIM:206200 iron-refractory iron deficiency anaemia pseudo-iron-deficiency Anemia MESH:C562385 pseudo-iron-deficiency Anaemia UMLS:C0085576 iron-refractory iron deficiency anemia anemia, hypochromic microcytic, with defect in iron metabolism IRIDA syndrome iron-handling disorder, hereditary IRIDA (Iron-refractory iron deficiency anemia) syndrome is a rare autosomal recessive iron metabolism disorder characterized by iron deficiency anemia (hypochromic, microcytic) that is often unresponsive to oral iron intake and partially responsive to parenteral iron treatment. SCTID:722005000 hereditary anemia