has material basis in germline mutation in ARG1 arginase deficiency https://github.com/monarch-initiative/mondo/issues/4985 https://github.com/monarch-initiative/mondo/issues/9097 https://www.malacards.org/card/argininemia OMIM:207800 GARD:0005840 NANDO:1200807 Orphanet:90 MESH:D020162 MONDO:0008814 UMLS:C0268548 DOID:9278 Arginase deficiency is a rare autosomal recessive amino acid metabolism disorder characterized clinically by variable degrees of hyperammonemia, developing from about 3 years of age, and leading to progressive loss of developmental milestones and spasticity in the absence of treatment. icd11.foundation:1619102598 NANDO:2200482 ICD10CM:E72.21 MedDRA:10062695 hyperargininemia NCIT:C84568 argininemia arginase deficiency SCTID:23501004 MEDGEN:78688 urea cycle disorder or inherited hyperammonemia