arthrogryposis-hyperkeratosis syndrome, lethal form https://www.malacards.org/card/arthrogryposis_hyperkeratosis_syndrome_lethal_form https://www.malacards.org/card/arthrogryposis_with_hyperkeratosis Orphanet:1485 OMIM:208158 SCTID:726620005 GARD:0003053 Johnston-Aarons-Schelley syndrome MONDO:0008826 MEDGEN:349230 Joint contractures, hyperkeratosis, and severe hypoplasia of the posterior columns MESH:C535883 Arthrogryposis-hyperkeratosis syndrome, lethal form is an arthrogryposis syndrome, described in two siblings to date, characterized by the association of multiple congenital joint contractures (of the large joints, fingers and toes) and hyperkeratosis (i.e. thick, scaling and fissured skin), with death occurring in early infancy. There have been no further reports in the literature since 1993. Johnston Aarons Schelley syndrome UMLS:C1859710 arthrogryposis multiplex congenita