has material basis in germline mutation in PRG4 rheumatic disorder autosomal recessive disease camptodactyly-arthropathy-coxa vara-pericarditis syndrome https://rarediseases.info.nih.gov/diseases/306/camptodactyly-arthropathy-coxa-vara-pericarditis-syndrome https://www.malacards.org/card/camptodactyly_arthropathy_coxa_vara_pericarditis_syndrome MEDGEN:349226 camptodactyly-arthropathy-coxa-vara-pericarditis syndrome pericarditis arthropathy camptodactyly syndrome PAC syndrome Jacobs syndrome DOID:0090127 CACP syndrome pericarditis-arthropathy-camptodactyly syndrome GARD:0000306 EFO:0009028 arthropathy-camptodactyly syndrome camptodactyly arthropathy pericarditis syndrome OMIM:208250 MESH:C537560 Orphanet:2848 camptodactyly-arthropathy-coxa vara-pericarditis syndrome UMLS:C1859690 camptodactyly arthropathy coxa vara pericarditis syndrome CACP arthropathy camptodactyly syndrome MONDO:0008828 fibrosing serositis, familial Camptodactyly-arthropathy-coxa-vara-pericarditis (CACP) syndrome is a rare, genetic, rheumatologic disease characterized by congenital or early-onset camptodactyly and symmetrical, polyarticular, non-inflammatory, large joint arthropathy with synovial hyperplasia, as well as progressive coxa vara deformity and, occasionally, non-inflammatory pericarditis. camptodactyly-arthropathy-pericarditis syndrome hereditary disorder of connective tissue