has material basis in germline mutation in CYP4V2 Bietti crystalline corneoretinal dystrophy https://rarediseases.info.nih.gov/diseases/10050/bietti-crystalline-corneoretinal-dystrophy https://www.malacards.org/card/bietti_crystalline_corneoretinal_dystrophy Bietti crystalline corneoretinal dystrophy OMIM:210370 Bietti crystalline retinopathy GARD:0010050 Orphanet:41751 MESH:C535440 SCTID:312927001 UMLS:C1859486 NCIT:C179299 DOID:0050664 Bietti's crystalline dystrophy (BCD) is a rare progressive autosomal recessive tapetoretinal degeneration disease, occurring in the third decade of life, characterized by small sparkling crystalline deposits in the posterior retina and corneal limbus in addition to sclerosis of the choroidal vessels and manifesting as nightblindness, decreased vision, paracentral scotoma, and, in the end stages of the disease, legal blindness. BCD MEDGEN:347895 MONDO:0008865 familial flecked retinopathy