has material basis in germline mutation in NT5E hereditary disease vascular disorder hereditary arterial and articular multiple calcification syndrome https://www.malacards.org/card/calcification_of_joints_and_arteries CALJA GARD:0010762 UMLS:C1859372 calcification of joints and arteries ACDC Orphanet:289601 SCTID:718602007 MONDO:0008895 DOID:0111582 MESH:C565891 MEDGEN:347132 arterial calcification and distal joint calcification arterial calcification due to CD73 deficiency Hereditary arterial and articular multiple calcification syndrome is a very rare genetic vascular disease of autosomal recessive inheritance, described in less than 20 patients to date, characterized by adult-onset (as early as the second decade of life) isolated calcification of the arteries of the lower extremities (including the iliac, femoral, and tibial arteries) as well as the capsule joints of the fingers, wrists, ankles and feet, and that usually manifests with mild paresthesias of the lower extremities, intense joint pain and swelling, and early onset arthritis of affected joints. OMIM:211800