has material basis in germline mutation in disease has basis in disruption of disease caused by disruption of SLC26A3 chloride transmembrane transporter activity secretory diarrhea congenital secretory chloride diarrhea 1 https://www.malacards.org/card/diarrhea_1_secretory_chloride_congenital secretory diarrhea caused by mutation in SLC26A3 familial chloride diarrhea OMIM:214700 SLC26A3 secretory diarrhoea MESH:C536210 SLC26A3 secretory diarrhea congenital chloride diarrhoea MONDO:0008964 congenital secretory chloride diarrhea type 1 congenital chloridorrhea ICD9:579.8 diarrhea 1, secretory chloride, congenital congenital secretory chloride diarrhoea type 1 familial chloride diarrhoea diarrhoea 1, secretory chloride, congenital SCTID:24412005 CLD secretory diarrhoea caused by mutation in SLC26A3 DOID:0060296 Darrow-gamble disease UMLS:C0267662 Orphanet:53689 DIAR1 MEDGEN:78631 GARD:0010001 Any secretory diarrhea in which the cause of the disease is a mutation in the SLC26A3 gene. congenital secretory diarrhea