has material basis in germline mutation in disease arises from structure disease arises from alteration in structure EXT1 chondrocyte sarcoma chondrosarcoma https://github.com/monarch-initiative/mondo/issues/4521 https://www.malacards.org/card/chondrosarcoma EFO:0000333 ONCOTREE:CHS HP:0006765 DOID:3371 NCIT:C2946 MONDO:0008977 chondrosarcoma (disease) Orphanet:55880 GARD:0006055 chondrosarcoma of bone chondrosarcoma (disease) MEDGEN:3054 chondrosarcoma MESH:D002813 ICDO:9220/3 ICD9:170.9 MedDRA:10008734 A malignant cartilaginous matrix-producing mesenchymal neoplasm arising from the bone and soft tissue. It usually affects middle-aged to elderly adults. The pelvic bones, ribs, shoulder girdle, and long bones are the most common sites of involvement. Most chondrosarcomas arise de novo, but some may develop in a preexisting benign cartilaginous lesion. OMIM:215300 chondrosarcoma, malignant NANDO:2200050 SCTID:443520009 chondrosarcoma, somatic mutation UMLS:C0008479 bone sarcoma connective tissue neoplasm hereditary disorder of connective tissue