has material basis in germline mutation in HSD11B2 adrenal gland disorder steroid inherited metabolic disorder adrenal gland hyperfunction apparent mineralocorticoid excess https://github.com/monarch-initiative/mondo/issues/4993 https://rarediseases.info.nih.gov/diseases/433/apparent-mineralocorticoid-excess https://www.malacards.org/card/apparent_mineralocorticoid_excess Apparent mineralocorticoid excess (AME) is a rare form of pseudohyperaldosteronism characterized by very early-onset and severe hypertension, associated with low renin levels and hypoaldosteronism. MESH:D043204 NANDO:2200362 apparent mineralocorticoid excess GARD:0000433 APE OMIM:218030 MEDGEN:90983 MONDO:0009025 Orphanet:320 DOID:4367 DOID:0090121 UMLS:C0342488 11-beta-hydroxysteroid dehydrogenase deficiency type 2 syndrome of apparent mineralocorticoid Excess NCIT:C131083 cortisol 11-beta-ketoreductase deficiency apparent mineralocorticoid excess syndrome SCTID:237770005 11 Beta-hydroxysteroid dehydrogenase type 2 deficiency NANDO:2100130 SCTID:703256004 icd11.foundation:1737310323 MESH:C537422 AME AME 1 Ulick syndrome ICD9:255.3 NCIT:C123231 obsolete genetic hypertension syndromic dyslipidemia