disease has major feature Dandy-Walker malformation-postaxial polydactyly syndrome https://www.malacards.org/card/dandy_walker_malformation_with_postaxial_polydactyly Pierquin syndrome DWM with postaxial polydactyly OMIM:220220 MEDGEN:341751 Dandy-Walker malformation with postaxial polydactyly syndrome is a syndromic disorder with, as a major feature, the association between Dandy-Walker malformation and postaxial polydactyly. The Dandy-Walker malformation has a variable expression and is characterized by a posterior fossa cyst communicating with the fourth ventricle, the partial or complete absence of the cerebellar vermis, and facultative hydrocephalus. Postaxial polydactyly includes tetramelic postaxial polydactyly of hands and feet with possible enlargement of the fifth metacarpal and metatarsal bones, as well as bifid fifth metacarpals. Orphanet:1566 SCTID:733094005 MONDO:0009075 UMLS:C1857351 MESH:C535771 GARD:0001669 central nervous system malformation