has characteristic has characteristic has material basis in germline mutation in TMPRSS15 hereditary disease digestive system disorder congenital enteropathy due to enteropeptidase deficiency https://github.com/monarch-initiative/mondo/issues/4069 https://www.malacards.org/card/enterokinase_deficiency GARD:0017038 SCTID:190952002 congenital enterokinase deficiency Orphanet:168601 ICD9:277.89 NANDO:2200910 DOID:0111667 UMLS:C0268416 MEDGEN:82802 OMIM:226200 MONDO:0009173 MESH:C562649 A rare, genetic, gastroenterological disease characterized by early-onset failure to thrive, edema, hypoproteinemia, diarrhea and fat malabsorption (or steatorrhea) in the presence of very low or absent trypsin activity in duodenal fluid. Celiac disease, or other pancreatic or mucosal disorders, may be associated. congenital