has material basis in germline mutation in TWIST2 focal facial dermal dysplasia type III https://www.malacards.org/card/focal_facial_dermal_dysplasia_3_setleis_type Focal facial dermal dysplasia type III (FFDD3) is a rare focal facial facial dysplasia (FFDD), characterized primarily by congenital bitemporal scar-like depressions and a typical, but variable facial dysmorphism, which may include distichiasis (upper lids) or lacking eyelashes, slanted eyebrows and a flattened and/or bulbous nasal tip and other features such as a low frontal hairline, sparse hair, redundant skin, epicanthal folds, low-set dysplastic ears, blepharitis and conjunctivitis. UMLS:C1744559 MEDGEN:315643 Orphanet:1807 FFDD type 2 Setleis syndrome FFDD type III bitemporal forceps marks syndrome SCTID:403771007 OMIM:227260 focal facial dermal dysplasia 3, Setleis type MONDO:0009203 GARD:0000121 FFDD3 focal facial dermal dysplasia type 2 focal facial dermal dysplasia type III focal facial dermal dysplasia