has material basis in germline mutation in PANK2 pantothenate kinase-associated neurodegeneration https://github.com/monarch-initiative/mondo/issues/9097 https://github.com/monarch-initiative/mondo/issues/9825 https://www.malacards.org/card/neurodegeneration_with_brain_iron_accumulation_1 neurodegeneration with brain iron accumulation type 1 MONDO:0009319 MEDGEN:6708 UMLS:C0018523 Orphanet:157850 neuroaxonal dystrophy, late infantile ICD9:333.0 MESH:D006211 GARD:0006564 PKAN DOID:3981 Pantothenate kinase-associated neurodegeneration (PKAN) is the most common type of neurodegeneration with brain iron accumulation (NBIA), a rare neurodegenerative disorder characterized by progressive extrapyramidal dysfunction (dystonia, rigidity, choreoathetosis), iron accumulation on the brain and axonal spheroids in the central nervous system. NORD:1550 NCIT:C84988 pigmentary pallidal degeneration neurodegeneration with brain iron accumulation 1 NANDO:2200886 NANDO:1200534 NBIA1 brain iron accumulation type I syndrome ICD10CM:G23.0 Hallervorden-Spatz disease pantothenate kinase-associated neurodegeneration SCTID:2992000 Hallervorden-Spatz syndrome OMIM:234200 neuroacanthocytosis neurodegeneration with brain iron accumulation