has characteristic has characteristic has material basis in germline mutation in SCN9A syndromic disease hereditary disease channelopathy-associated congenital insensitivity to pain, autosomal recessive https://github.com/monarch-initiative/mondo/issues/4069 https://github.com/monarch-initiative/mondo/issues/4521 https://github.com/monarch-initiative/mondo/issues/6877 https://www.malacards.org/card/indifference_to_pain_congenital_autosomal_recessive MONDO:0009459 MEDGEN:344563 OMIM:243000 HSAN2D indifference to pain, congenital, autosomal recessive channelopathy-associated CIP CIP UMLS:C1855739 insensitivity to pain, congenital Orphanet:88642 GARD:0012267 A syndrome characterized by indifference to pain despite the ability to distinguish noxious from non-noxious stimuli. Absent corneal reflexes and intellectual disability may be associated. Familial forms with autosomal recessive and autosomal dominant patterns of inheritance have been described. (Adams et al., Principles of Neurology, 6th ed, p1343) congenital