has material basis in germline mutation in PCDH12 diencephalic-mesencephalic junction dysplasia syndrome 1 https://rarediseases.info.nih.gov/diseases/8510/microcephaly-with-spastic-quadriplegia https://www.malacards.org/card/diencephalic_mesencephalic_junction_dysplasia_syndrome_1 DMJDS1 MEDGEN:1615973 MONDO:0009625 microcephaly with spastic quadriplegia GARD:0008510 MESH:C537546 recessive microcephaly with spastic quadriplegia MISSBC OMIM:251280 UMLS:C4538630 diencephalic-mesencephalic junction dysplasia