has material basis in germline mutation in disease has basis in disruption of disease caused by disruption of ARSB N-acetylgalactosamine-4-sulfatase activity syndromic disease eye disorder mucopolysaccharidosis type 6 https://github.com/monarch-initiative/mondo/issues/4521 https://github.com/monarch-initiative/mondo/issues/4948 https://www.malacards.org/card/mucopolysaccharidosis_type_vi Maroteaux Lamy syndrome SCTID:52677002 MPS6 NANDO:1200109 NANDO:1200108 mucopolysaccharidosis type VI (Maroteaux-Lamy) arylsulfatase B deficiency icd11.foundation:1288379621 OMIM:253200 NCIT:C61264 DOID:12800 GARD:0007095 ASB deficiency UMLS:C0026709 Orphanet:583 MESH:D009087 MedDRA:10056892 Mucopolysaccharidosis type 6 (MPS 6) is a lysosomal storage disease with progressive multisystem involvement, associated with a deficiency of arylsulfatase B (ASB) leading to the accumulation of dermatan sulfate. Maroteaux-Lamy syndrome NANDO:2200551 ARSB deficiency SCTID:69463008 Maroteaux-Lamy disease Maroteaux Lamy Syndrome NORD:1405 mucopolysaccharidosis type VI MEDGEN:44514 MPSVI Mucopoly-saccharidosis type VI NANDO:1200110 MONDO:0009661 N-acetylgalactosamine 4-sulfatase deficiency MPS VI mucopolysaccharidosis lysosomal storage disease with skeletal involvement