hypothyroidism myxedema https://www.malacards.org/card/myxedema OMIM:255900 EFO:1001055 NCIT:C34834 Editor note: myxedema can also refer to a dermatological change that can occur in hypothyroidism and some forms of hyperthyroidism. MedDRA:10028663 DOID:11634 myxedema UMLS:C0027145 SCTID:43153006 MEDGEN:6506 MESH:D009230 A condition characterized by severe hypothyroidism that is caused by autoimmune thyroid gland disorders, surgical reduction of thyroid tissue, radiation exposure, and viral infections. Signs and symptoms include generalized fatigue, lethargy, increased body weight, pale, edematous and thickened skin, low blood pressure, constipation and cold intolerance. MONDO:0009718