syndromic disease ichthyosis-oral and digital anomalies syndrome https://github.com/monarch-initiative/mondo/issues/6749 https://github.com/monarch-initiative/mondo/issues/6877 https://github.com/monarch-initiative/mondo/issues/6878 https://www.malacards.org/card/oral_and_digital_anomalies_with_ichthyosis MESH:C536272 MONDO:0009792 OMIM:258840 Clayton Smith-Donnai syndrome unusual facies, digital abnormalities, and ichthyosis Ichthyosis-oral and digital anomalies syndrome is characterized by ichthyosis, unusual facies (small mouth with a thin upper lip and lower lip with a midline groove) and digital anomalies (tapered fingers with a lack of distal flexion creases and wide spacing between the second and third fingers). It has been described in two sibs born to first cousin parents. Transmission appears to be autosomal recessive. Orphanet:2272 UMLS:C1850268 oral and digital anomalies with ichthyosis MEDGEN:342457 ichthyosis tapered fingers midline groove up GARD:0002960 multiple congenital anomalies/dysmorphic syndrome without intellectual disability inherited ichthyosis