has material basis in germline mutation in disease has basis in disruption of disease caused by disruption of SARDH sarcosine dehydrogenase activity sarcosinemia https://github.com/monarch-initiative/mondo/issues/4521 https://github.com/monarch-initiative/mondo/issues/4985 https://github.com/monarch-initiative/mondo/issues/9285 https://rarediseases.info.nih.gov/diseases/158/sarcosinemia https://www.malacards.org/card/sarcosinemia GARD:0000158 SCTID:64852002 MONDO:0010008 Sarcosinemia is a metabolic disorder characterized by an increased concentration of sarcosine in plasma and urine due to sarcosine dehydrogenase deficiency. MEDGEN:120651 ICD9:270.8 MedDRA:10059299 icd11.foundation:1901733714 sarcosinemia Orphanet:3129 UMLS:C0268563 MESH:C537236 OMIM:268900 DOID:0112307 SARCOS inborn disorder of serine family metabolism disorder of methylamine metabolism