has material basis in germline mutation in GGCX vitamin K-dependent clotting factors, combined deficiency of, type 1 https://github.com/monarch-initiative/mondo/issues/6750 https://www.malacards.org/card/vitamin_k_dependent_clotting_factors_combined_deficiency_of_1 vitamin K-dependent clotting factors, combined deficiency of, type 1 MONDO:0010187 multiple coagulation Factor deficiency 3 SCTID:724356003 hereditary combined deficiency of vitamin K-dependent clotting factors vitamin K-dependent coagulation defect Combined vitamin K-dependent clotting factors deficiency (VKCFD) is a congenital bleeding disorder resulting from variably decreased levels of coagulation factors II, VII, IX and X, as well as natural anticoagulants protein C, protein S and protein Z. factors II, VII, IX, and X, combined deficiency of This term's classification was reviewed in the context of the Strategic Refinement project (2023) and was determined to be excluded from the 'metabolic disease' (MONDO:0005066) ontology branch (https://orcid.org/0000-0002-1780-5230) familial multiple coagulation Factor deficiency 3 Vkcfd FMFD 3 MEDGEN:376381 VKCFD1 UMLS:C1848534 GGCX congenital vitamin K-dependent coagulation factors combined deficiency hereditary combined deficiency of factors II, VII, IX and X vitamin K-dependent clotting factors, combined deficiency of, 1 DOID:0112173 congenital vitamin K-dependent coagulation factors combined deficiency caused by mutation in GGCX GARD:0018195 glutamic acid, deficient gamma-carboxylation of OMIM:277450 MESH:C564741 congenital vitamin K-dependent coagulation factors deficiency