has material basis in germline mutation in FLNA hereditary disease intestinal pseudoobstruction, neuronal, chronic idiopathic, X-linked https://github.com/monarch-initiative/mondo/issues/4521 https://rarediseases.info.nih.gov/diseases/3017/intestinal-pseudoobstruction-neuronal-chronic-idiopathic-x-linked https://www.malacards.org/card/intestinal_pseudoobstruction_neuronal_chronic_idiopathic_x_linked_2 https://www.malacards.org/card/x_linked_chronic_idiopathic_intestinal_pseudo_obstruction Intestinal pseudo-obstruction is a condition characterized by impairment of the muscle contractions that move food through the digestive tract. The condition may arise from abnormalities of the gastrointestinal muscles themselves (myogenic) or from problems with the nerves that control the muscle contractions (neurogenic). When intestinal pseudo-obstruction occurs by itself, it is called primary or idiopathic (unknown cause) intestinal pseudo-obstruction. The disorder can also develop as a complication of another medical condition; in these cases, it is called secondary intestinal pseudo-obstruction. Individuals with this condition have symptoms that resemble those of an intestinal blockage (obstruction) but without any obstruction. It may be acute or chronic and is characterized by the presence of dilation of the bowel on imaging. The causes may be unknown or due to alterations (mutations) in the FLNA gene, other genes or are secondary to other conditions. It may be inherited in some cases. Intestinal pseudoobstruction neuronal chronic idiopathic X-linked is caused by alterations (mutations) in the FLNA gene which is located in the X chromosome. There is no specific treatment but several medications and procedures may be used to treat the symptoms. congenital short bowel syndrome, X-linked recessive MONDO:0010232 intestinal pseudoobstruction, neuronal, X-linked recessive CIIPX GARD:0003017 DOID:0080681 intestinal pseudoobstruction neuronal chronic idiopathic X-linked MEDGEN:412536 CIIP X-linked CIIP MESH:C535532 OMIM:300048 intestinal pseudoobstruction, neuronal, chronic idiopathic, X-linked UMLS:C2746068 congenital short bowel syndrome chronic intestinal pseudoobstruction idiopathic disease