has characteristic has characteristic has material basis in germline mutation in WAS X-linked inheritance X-linked disease X-linked severe congenital neutropenia https://github.com/monarch-initiative/mondo/issues/4521 https://rarediseases.info.nih.gov/diseases/3981/severe-congenital-neutropenia-x-linked https://www.malacards.org/card/neutropenia_severe_congenital_x_linked MONDO:0010294 OMIM:300299 NANDO:2200753 GARD:0003981 Xln UMLS:C1845987 Orphanet:86788 neutropenia, severe congenital, X-linked DOID:0112128 severe congenital neutropenia, X-linked MEDGEN:335314 SCTID:718882006 This syndrome is an immunodeficiency syndrome characterized by recurrent major bacterial infections, severe congenital neutropenia, and monocytopenia. It has been described in five males spanning three generations of one family. It is transmitted as an X-linked recessive trait and is caused by mutations in the WAS gene, encoding the WASP protein. MESH:C564539 SCNX X-linked severe congenital neutropenia neutropenia, severe congenital, X-linked, X-linked recessive severe congenital neutropenia X-linked severe congenital neutropenia