hereditary spastic paraplegia 34 https://github.com/monarch-initiative/mondo/issues/4521 https://github.com/monarch-initiative/mondo/issues/6752 https://www.malacards.org/card/spastic_paraplegia_34_x_linked GARD:0017063 OMIM:300750 SCTID:763370008 MEDGEN:437069 SPG34 hereditary spastic paraplegia type 34 DOID:0110785 MESH:C567465 spastic paraplegia 34, X-linked, X-linked recessive MONDO:0010418 spastic paraplegia 34, X-linked X-linked spastic paraplegia type 34 is a pure form of hereditary spastic paraplegia characterized by late childhood- to early adulthood-onset of slowly progressive spastic paraplegia with spastic gait and lower limb hyperreflexia, brisk tendon reflexes and ankle clonus. Lower limb pain and reduced lower limb vibratory sense is also reported in some older adult patients. Orphanet:171607 UMLS:C2677897 X-linked spastic paraplegia type 34 pure hereditary spastic paraplegia