Charcot-Marie-Tooth disease X-linked dominant 6 https://github.com/monarch-initiative/mondo/issues/4521 https://www.malacards.org/card/charcot_marie_tooth_disease_x_linked_dominant_6 Charcot-Marie-Tooth disease, X-linked dominant, 6, X-linked dominant DOID:0110207 CMT6X UMLS:C3806702 Charcot-Marie-Tooth disease, X-linked dominant, type 6 GARD:0012445 Orphanet:352675 CMTX6 X-linked Charcot-Marie-Tooth disease type 6 is a rare, genetic, principally axonal, peripheral sensorimotor neuropathy characterized by an X-linked dominant inheritance pattern and the childhood-onset of slowly progressive, moderate to severe, distal muscle weakness and atrophy of the lower extremities, as well as distal, panmodal sensory abnormalities, bilateral foot deformities (pes cavus, clawed toes), absent ankle reflexes and gait abnormalities (steppage gait). Females are usually asymptomatic or only present mild manifestations (mild postural hand tremor, mild wasting of hand intrinsic muscles). Editor note: check CMT6X synonym, this implies it is a subtype of CMT6 OMIM:300905 SCTID:763347000 MONDO:0010479 Charcot-Marie-Tooth disease X-linked dominant type 6 MEDGEN:813032 Charcot-Marie-Tooth disease, X-linked dominant, 6 X-linked Charcot-Marie-Tooth disease type 6 Charcot-Marie-Tooth disease type X