Mononen-Karnes-Senac syndrome https://rarediseases.info.nih.gov/diseases/4886/brachydactyly-mononen-type https://www.malacards.org/card/brachydactyly_mononen_type_2 skeletal dysplasia-brachydactyly syndrome skeletal dysplasia brachydactyly MEDGEN:336815 Mononen-Karnes-Senac syndrome is characterized by skeletal dysplasia associated with finger malformations (brachydactyly with short and abducted thumbs, short index fingers, and markedly short and abducted great toes), variable mild short stature, and mild bowleg with overgrowth of the fibula. It has been described in two males, their mothers, and a maternal aunt. Females are less severely affected than males. X-linked dominant inheritance is suggested. UMLS:C1844919 thumbs and great toes short and abducted Mononen Karnes Senac syndrome MONDO:0010538 MESH:C535914 Orphanet:2565 SCTID:733095006 DOID:0110973 brachydactyly Mononen type OMIM:301940 GARD:0004886 congenital limb malformation