has material basis in germline mutation in disease has basis in disruption of disease caused by disruption of STS steryl-sulfatase activity recessive X-linked ichthyosis https://github.com/monarch-initiative/mondo/issues/2114 https://github.com/monarch-initiative/mondo/issues/4521 https://github.com/monarch-initiative/mondo/issues/9097 https://github.com/monarch-initiative/mondo/issues/9285 https://www.malacards.org/card/ichthyosis_x_linked Orphanet:461 There are both syndromic and non-syndromic forms of this disease (PMID:20643494). MONDO:0010622 Ichthyosis, X Linked UMLS:C0079588 X-linked ichthyosis ichthyosis , X-linked, X-linked recessive DOID:1700 NCIT:C84779 DECIPHER:27 GARD:0007904 OMIM:308100 XLI SSDD X linked ichthyosis ichthyosis (disease), X-linked MEDGEN:86937 ICD10CM:Q80.1 ichthyosis, X-linked NANDO:1200625 steroid sulfatase deficiency A genodermatosis belonging to the Mendelian Disorders of Cornification (MeDOC) and characterized by generalized hyperkeratosis and scaling of the skin. recessive X-linked ichthyosis X-linked recessive ichthyosis icd11.foundation:1466487054 MedDRA:10048063 RXLI SCTID:3944006 NORD:1293 inherited ichthyosis sterol metabolism disorder X-linked recessive disease