has material basis in germline mutation in disease has feature ATP7A Abnormal eyelash morphology Abnormal eyebrow morphology syndromic disease disorder of pilosebaceous unit inborn metal metabolism disorder Menkes disease https://github.com/monarch-initiative/mondo/issues/4521 https://rarediseases.info.nih.gov/diseases/1521/menkes-disease https://www.malacards.org/card/menkes_disease Menkes kinky hair syndrome Menkes syndrome GARD:0001521 menkes disease, X-linked recessive OMIM:309400 X-linked copper deficiency Menkes disease NANDO:1200653 MESH:D007706 MEDGEN:44030 kinky hair syndrome ICD9:759.89 DOID:1838 A usually severe multisystemic disorder of copper metabolism, characterized by progressive neurodegeneration and marked connective tissue anomalies as well as typical sparse abnormal steely hair. MedDRA:10027294 copper transport disease MNK Mk UMLS:C0022716 steely hair disease Menkea syndrome Menkes kinky-hair syndrome kinky hair disease MONDO:0010651 Orphanet:565 NCIT:C75486 NORD:1440 SCTID:59178007 NANDO:2200580 icd11.foundation:986728180 Trichopoliodystrophy MD disorder of copper metabolism obsolete syndromic hair shaft abnormality obsolete eyebrow/eyelashes structural anomaly