has material basis in germline mutation in IQSEC2 intellectual disability, X-linked 1 https://github.com/monarch-initiative/mondo/issues/4521 https://github.com/monarch-initiative/mondo/issues/7283 https://www.malacards.org/card/intellectual_developmental_disorder_x_linked_1 https://www.malacards.org/card/non_syndromic_x_linked_intellectual_disability_1 https://www.malacards.org/card/severe_intellectual_disability_progressive_postnatal_microcephaly_midline_stereotypic_hand_movements_syndrome_2 mental retardation, X-linked type 1 mental retardation, X-linked 18 DOID:0112038 MONDO:0010656 UMLS:C2931498 X-linked intellectual disability 1/78 OMIM:309530 MESH:C567906 Orphanet:397933 MRX78 IQSEC2-related syndromic intellectual disability MRX1 X-linked intellectual disability 78 IQSEC2-related disorder IQSEC2-related epilepsy MESH:C564489 intellectual disability, X-linked 1 An X-linked dominant condition caused by mutation(s) in the IQSEC2 gene, encoding IQ motif and SEC7 domain-containing protein 2. It is characterized by substantially impaired intellectual functioning and behavioral abnormalities. mental retardation, X-linked 78 IQSEC2 IQSEC2-related intellectual disability NCIT:C133729 MEDGEN:444070 GARD:0022699 X-linked intellectual disability 1 mental retardation, X-linked 1 MRX intellectual developmental disorder, X-linked 1, X-linked dominant non-syndromic X-linked intellectual disability X-linked syndromic intellectual disability