has material basis in germline mutation in RAB39B early-onset parkinsonism-intellectual disability syndrome https://github.com/monarch-initiative/mondo/issues/4521 https://github.com/monarch-initiative/mondo/issues/5588 https://github.com/monarch-initiative/mondo/issues/9285 https://www.malacards.org/card/waisman_syndrome basal ganglia disorder with intellectual disability Parkinsonism, early onset with intellectual disability OMIM:311510 UMLS:C0796195 Orphanet:2379 X-linked recessive basal ganglia disorder with mental retardation WSMN DOID:0111781 Waisman syndrome basal ganglion disorder with mental retardation X-linked recessive basal ganglia disorder with intellectual disability early-onset parkinsonism-intellectual disability syndrome SCTID:716107009 Laxova-Opitz syndrome WAISMAN syndrome icd11.foundation:937544163 Laxova Brown hogan syndrome Parkinsonism, early-onset, with mental retardation Waisman syndrome, X-linked recessive GARD:0003203 basal ganglia disorder with mental retardation MEDGEN:208674 MONDO:0010709 MESH:C537179 A basal ganglia disorder characterized by Parkinsonian-type symptoms (postural changes, tremor, rigidity), megalencephaly and variable intellectual deficit. Other signs are frontal bossing, persistent frontal lobe reflexes, strabismus and seizures. It has been described in three generations of one family. Transmission is X-linked, and the gene is located on chromosomal region Xq27.3-qter. BGMR Parkinsonism, early onset with mental retardation X-linked syndromic intellectual disability parkinsonian disorder