disease has feature disease has major feature Irritability Anxiety Pallor Lethargy Nausea and vomiting Abdominal pain Headache cyclic vomiting syndrome https://www.malacards.org/card/cyclic_vomiting_syndrome cyclic vomiting syndrome with neuromuscular disease UMLS:C0152164 NANDO:2200919 Cvs-plus cyclic vomiting syndrome-plus icd11.foundation:1434288855 MONDO:0010778 OMIM:500007 A rare functional disorder characterized by recurrent, stereotypical episodes of severe nausea and vomiting separated by symptom-free intervals. Episodes are often accompanied by pallor, lethargy, and abdominal pain. The condition shows a strong association with migraine headaches and may have maternal inheritance patterns suggestive of mitochondrial involvement. NANDO:2100258 cyclic vomiting syndrome CVS MEDGEN:57509 neuroendocrine disorder