disease has feature Hypotonia Dysharmonic delayed bone age syndromic intellectual disability syndromic disease Qazi Markouizos syndrome https://github.com/monarch-initiative/mondo/issues/5588 https://rarediseases.info.nih.gov/diseases/371/qazi-markouizos-syndrome https://www.malacards.org/card/puerto_rican_infant_hypotonia_syndrome https://www.malacards.org/card/qazi_markouizos_syndrome OMIM:600096 Qazi-Markouizos syndrome is characterized principally by non-progressive central hypotonia, chronic constipation, severe psychomotor retardation, abnormal dermatoglyphics, dysharmonic skeletal maturation and disproportionate muscle fibers. Seizures or an abnormal electroencephalograph were also reported. To date, the syndrome has been reported in three unrelated Puerto Rican boys. Dysharmonic skeletal maturation-muscular fibre disproportion syndrome hypotonia, psychomotor retardation, seizures, delayed and Dysharmonic skeletal maturation, and congenital fiber type disproportion GARD:0000371 MESH:C536259 PUERTO RICAN infant hypotonia syndrome Dysharmonic skeletal maturation muscular fiber disproportion DOID:0050740 MONDO:0010816 Puertorican infant hypotonia syndrome Dysharmonic skeletal maturation - muscular fiber disproportion Dysharmonic skeletal maturation muscular fibre disproportion Dysharmonic skeletal maturation-muscular fiber disproportion syndrome SCTID:721887007 MEDGEN:443987 UMLS:C2931142 Qazi-Markouizos syndrome hypotonia, psychomotor retardation, seizures, delayed and Dysharmonic skeletal maturation, and congenital fibre type disproportion Orphanet:3010