motor peripheral neuropathy Charcot-Marie-Tooth disease type 5 https://www.malacards.org/card/charcot_marie_tooth_disease_type_5 https://www.malacards.org/card/hereditary_motor_and_sensory_neuropathy_v UMLS:C4721916 GARD:0009208 DOID:0080067 MEDGEN:1648461 SCTID:76043009 Charcot-Marie-Tooth disease-pyramidal features syndrome Hereditary motor and sensory neuropathy type 5 is a rare axonal hereditary motor and sensory neuropathy characterized by slowly progressive distal muscle weakness and atrophy with or without sensory loss resulting in difficulty in walking, foot drop and pes cavus, that may be associated with pyramidal signs (extensor plantar responses, mild increase in tone, brisk tendon reflexes), muscle cramps, pain and spasticity. OMIM:600361 hereditary motor and sensory neuropathy 5 MONDO:0010877 HMSN5 Orphanet:64751 HMSN 5 hereditary motor and sensory neuropathy type 5 hereditary spastic paraplegia hereditary peripheral neuropathy