syndromic disease HEC syndrome https://rarediseases.info.nih.gov/diseases/2620/hec-syndrome https://www.malacards.org/card/hydrocephalus_endocardial_fibroelastosis_and_cataracts hydrocephalus-endocardial fibroelastosis-cataract syndrome Orphanet:2119 MESH:C535855 GARD:0002620 MEDGEN:331549 OMIM:600559 communicating hydrocephalus, endocardial fibroelastosis (EFE) and congenital cataracts MONDO:0010901 Editor note: Orphanet classifies as both familial and non-familial, dilated and restrictive cardiomyopathy hydrocephalus, endocardial fibroelastosis, and cataracts UMLS:C1833607 SCTID:721015008 HEC syndrome is characterized by communicating hydrocephalus, endocardial fibroelastosis (EFE), and congenital cataracts. It has been described in two children, both of whom died a few months after birth (the first as a result of a respiratory infection and the second due to cardiac complications). The etiology of the syndrome is unknown but a viral or genetic origin has been proposed. HEC syndrome