has material basis in germline mutation in POMP keratosis linearis-ichthyosis congenita-sclerosing keratoderma syndrome https://github.com/monarch-initiative/mondo/issues/6749 https://github.com/monarch-initiative/mondo/issues/6877 https://www.malacards.org/card/keratosis_linearis_with_ichthyosis_congenita_and_sclerosing_keratoderma GARD:0017306 MEDGEN:356430 MONDO:0011169 UMLS:C1866029 Orphanet:281201 SCTID:763775000 Keratosis linearis-ichthyosis congenita-sclerosing keratoderma (KLICK) syndrome is an inherited epidermal disorder characterized by palmoplantar keratoderma, linear hyperkeratotic papules on the flexural side of large joints (cord-like distribution around wrists, in antecubital and popliteal folds), hyperkeratotic plaques (on neck, axillae, elbows, wrists, and knees), mild ichthyosiform scaling, and sclerotic constrictions around fingers that present flexural deformities. Klick syndrome keratosis linearis-ichthyosis congenita-sclerosing keratoderma syndrome OMIM:601952 keratosis linearis with ichthyosis congenita and sclerosing keratoderma KLICK syndrome MESH:C566600 KLICK epidermal disease hereditary skin disorder