has material basis in germline mutation in SPG11 familial amyotrophic lateral sclerosis amyotrophic lateral sclerosis type 5 https://rarediseases.info.nih.gov/diseases/10503/amyotrophic-lateral-sclerosis-type-5 https://www.malacards.org/card/amyotrophic_lateral_sclerosis_5_juvenile https://www.malacards.org/card/amyotrophic_lateral_sclerosis_type_5 DOID:0060197 GARD:0015343 OMIM:602099 ALS5 MESH:C566576 amyotrophic lateral sclerosis 5, juvenile UMLS:C1865864 SPG11 amyotrophic lateral sclerosis MONDO:0011196 amyotrophic lateral sclerosis caused by mutation in SPG11 MEDGEN:356388 Any amyotrophic lateral sclerosis in which the cause of the disease is a mutation in the SPG11 gene. juvenile amyotrophic lateral sclerosis