has material basis in germline mutation in PRF1 familial hemophagocytic lymphohistiocytosis 2 https://rarediseases.info.nih.gov/diseases/9922/hemophagocytic-lymphohistiocytosis-familial-2 https://www.malacards.org/card/hemophagocytic_lymphohistiocytosis_familial_2 GARD:0009922 HLH2 HPLH2 MEDGEN:400366 genetic hemophagocytic lymphohistiocytosis caused by mutation in PRF1 MONDO:0011337 hemophagocytic lymphohistiocytosis, familial, type 2 familial hemophagocytic lymphohistiocytosis type 2 Hlh2 PRF1 genetic hemophagocytic lymphohistiocytosis DOID:0110922 MESH:C537250 OMIM:603553 UMLS:C1863727 Any genetic hemophagocytic lymphohistiocytosis in which the cause of the disease is a mutation in the PRF1 gene. hemophagocytic lymphohistiocytosis, familial, 2 FHL2 NANDO:2200728 Hplh2 hereditary hemophagocytic lymphohistiocytosis