has material basis in germline mutation in FBN1 MASS syndrome https://rarediseases.info.nih.gov/diseases/8489/mass-syndrome Mitral valve prolapse, Aortic enlargement, Skin and Skeletal findings OMIM:604308 MESH:C536030 UMLS:C1858556 MASS syndrome GARD:0008489 Orphanet:99715 MEDGEN:346932 OCTD A genetic disorder of connective tissue caused by mutations in the FBN1 gene. Connective tissue is the material between the cells of the body that gives tissues form and strength. Symptoms include mitral valve prolapse, nearsightedness, borderline and non-progressive aortic enlargement, and skin and skeletal findings that overlap with those seen in Marfan syndrome. Treatment is based on the individuals symptoms. MASS phenotype MONDO:0011431 overlapping connective tissue disease hereditary disorder of connective tissue