has material basis in germline mutation in C1QTNF5 late-onset retinal degeneration https://www.malacards.org/card/late_onset_retinal_degeneration pigmentary retinopathy Late-onset retinal degeneration is an inherited retinal dystrophy characterized by delayed dark adaptation and nyctalopia and drusen deposits presenting in adulthood, followed by cone and rod degeneration that presents in the sixth decade of life, which leads to central vision loss. Anterior segment features such as peripupillary iris transillumination defects and abnormally long anterior zonular insertions are also observed. Choroidal neovascularization and glaucoma may occur in the late stages of the disease. SCTID:719431007 retinal Degeneration, late-onset, autosomal dominant LORD OMIM:605670 autosomal dominant late-onset retinal degeneration UMLS:C1854065 MONDO:0011579 GARD:0004357 DOID:0060869 late-onset retinal degeneration MESH:C565309 Orphanet:67042 MEDGEN:344198 inherited retinal dystrophy