has material basis in germline mutation in ELMO2 hereditary disease primary intraosseous venous malformation https://www.malacards.org/card/primary_intraosseous_venous_malformation https://www.malacards.org/card/vascular_malformation_primary_intraosseous MONDO:0011744 Primary intraosseous venous malformation is a rare, genetic vascular anomaly characterized by severe blood vessel expansion (most frequently within the craniofacial bones) with painless bone enlargement (usually of mandibule, maxilla and/or orbital, nasal, and frontal bones), typically resulting in facial asymmetry and contour deformation. Midline abnormalities, such as diastasis recti, supraumbilical raphe, and hiatus hernia, are commonly associated. Additional features reported include gingival bleeding, ectopic tooth eruption, exophthalmos, loss of vision, nausea, and vomiting. osseous venous malformation SCTID:764100007 MESH:C564648 MEDGEN:376071 GARD:0016961 UMLS:C1847197 OMIM:606893 intraosseous hemangioma Orphanet:140436 infantile hemangioma of rare localization